منابع مشابه
A Review: Polymeric In-situ Gel System
Smart polymeric systems represent promising means of delivering the drugs; these polymers undergo sol-gel transition, once administered. In-situ gel structure occurs due to one or combination of different stimuli like pH change, temperature modulation and ionic exchange. The formation of gels depends on factors like temperature modulation, pH change, presence of ions and ultra violet irradiatio...
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Calsequestrin (CASQ) is the major component of the sarcoplasmic reticulum (SR) lumen in skeletal and cardiac muscles. This calcium binding protein localizes to the junctional SR (jSR) cisternae where it is responsible for the storage of large amounts of Ca 2+ while it is usually absent, at least in its polymerized form, in the free SR. The retention of CASQ inside the jSR is partly due to its a...
متن کاملA Novel Approach In-Situ Gel for Sustained Drug Delivery: A Review
Sustained drug delivery has become the standard in modern Pharmaceutical design and an intensive research has been undertaken in achieving much better drug product effectiveness, reliability and safety. This interest has been sparked by the advantages shown by in-situ forming polymeric delivery systems such as ease of administration and reduced frequency of administration, improved patient comp...
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The oral delivery of drugs with a narrow absorption window in the gastrointestinal tract (GIT) is often limited by poor bioavailability with conventional dosage forms due to incomplete drug release and short residence time at the site of absorption. In-situ gel provides the best way to overcome problems of immediate release and short gastrointestinal residence of liquids. The in situ gel dosage...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical and Biological Research
سال: 2016
ISSN: 2320-9267
DOI: 10.30750/ijpbr.4.2.2